Invention Grant
- Patent Title: Modulation of huntingtin expression
- Patent Title (中): 调节亨廷顿蛋白的表达
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Application No.: US14528656Application Date: 2014-10-30
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Publication No.: US09273315B2Publication Date: 2016-03-01
- Inventor: Gene Hung , C. Frank Bennett , Susan M. Freier , Holly Kordasiewicz , Lisa Stanek , Don W. Cleveland , Seng H. Cheng , Lamya Shihabuddin
- Applicant: Isis Pharmaceuticals, Inc.
- Applicant Address: US CA Carlsbad
- Assignee: Ionis Pharmaceuticals, Inc.
- Current Assignee: Ionis Pharmaceuticals, Inc.
- Current Assignee Address: US CA Carlsbad
- Agency: McNeill Baur PLLC
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N15/113
Abstract:
Provided herein are methods, compounds, and compositions for reducing expression of huntingtin mRNA and protein in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate Huntington's disease, or a symptom thereof.
Public/Granted literature
- US20150159155A1 MODULATION OF HUNTINGTIN EXPRESSION Public/Granted day:2015-06-11
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