Invention Grant
- Patent Title: B cell maturation antigen (BCMA) binding proteins
- Patent Title (中): B细胞成熟抗原（BCMA）结合蛋白
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Application No.: US13795314Application Date: 2013-03-12
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Publication No.: US09273141B2Publication Date: 2016-03-01
- Inventor: Paul Algate , Stephanie Jane Clegg , Jennifer L. Craigen , Paul Andrew Hamblin , Alan Peter Lewis , Patrick Mayes , Radha Shah Parmar , Trevor Anthony Kenneth Wattam
- Applicant: Glaxo Group Limited
- Applicant Address: GB Brentford, Middlesex
- Assignee: Glaxo Group Limited
- Current Assignee: Glaxo Group Limited
- Current Assignee Address: GB Brentford, Middlesex
- Agent Elizabeth J. Hecht; Edward J. Gimmi
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C07K16/28 ; C07K16/30 ; A61K39/00
Abstract:
The present invention concerns antigen binding proteins and fragments thereof which specifically bind B Cell Maturation Antigen (BCMA), particularly human BCMA (hBCMA) and which inhibit the binding of BAFF and APRIL to the BCMA receptor. Further disclosed are pharmaceutical compositions, screening and medical treatment methods.
Public/Granted literature
- US20130280280A1 ANTIGEN BINDING PROTEINS Public/Granted day:2013-10-24
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