Invention Grant
- Patent Title: Recombinant human G-CSF dimer and use thereof for the treatment of neurological diseases
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Application No.: US14014413Application Date: 2013-08-30
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Publication No.: US09273108B2Publication Date: 2016-03-01
- Inventor: Xiaoqiang Yan , Zhihua Huang , Hongzhou Yang , Bill N. C. Sun , Yuliang Huang
- Applicant: Generon (Shanghai) Corporation Ltd.
- Applicant Address: CN Shanghai
- Assignee: Generon (Shanghai) Corporation Ltd.
- Current Assignee: Generon (Shanghai) Corporation Ltd.
- Current Assignee Address: CN Shanghai
- Agency: Morrison & Foerster LLP
- Priority: CN201010181623 20100525
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C07K14/535 ; C12N15/09 ; C12N15/24 ; A61P25/00 ; A61K38/19
Abstract:
This invention relates to a recombinant human G-CSF (rhG-CSF) dimer and its use in the treatment of neurological disorder. In particular, upon ischemic neural injury in animal, this invention can be used to protect neurons with the use of rhG-CSF dimer such that function of injured nerves can be restored. Serum half-life of G-CSF dimer of this invention is prolonged and the biological activity thereof is increased.
Public/Granted literature
- US20140004076A1 RECOMBINANT HUMAN G-CSF DIMER AND USE THEREOF FOR THE TREATMENT OF NEUROLOGICAL DISEASES Public/Granted day:2014-01-02
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