Invention Grant
US09272055B2 Functionalized magnetic nanoparticles and use in imaging amyloid deposits and neurofibrillary tangles
有权
功能磁性纳米粒子,用于成像淀粉样沉积物和神经原纤维缠结
- Patent Title: Functionalized magnetic nanoparticles and use in imaging amyloid deposits and neurofibrillary tangles
- Patent Title (中): 功能磁性纳米粒子,用于成像淀粉样沉积物和神经原纤维缠结
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Application No.: US14007298Application Date: 2012-04-04
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Publication No.: US09272055B2Publication Date: 2016-03-01
- Inventor: Massoud Akhtari
- Applicant: Massoud Akhtari
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Bozicevic, Field & Francis LLP
- Agent Paula A. Borden
- International Application: PCT/US2012/032100 WO 20120404
- International Announcement: WO2012/145169 WO 20121026
- Main IPC: A61K31/44
- IPC: A61K31/44 ; A61K31/277 ; A61K49/10 ; A61K31/4745 ; A61K31/132 ; A61K31/133 ; A61K31/136 ; A61K31/145 ; A61K31/167 ; A61K31/427 ; A61K31/428 ; A61K31/4439 ; A61K31/444 ; A61K31/472 ; A61K49/18

Abstract:
The present disclosure provides functionalized magnetic nanoparticles (MNPs) comprising a functional group that binds to β-amyloid deposits and/or neurofibrillary tangles. The present disclosure provides compositions comprising the functionalized MNPs, and methods of using the functionalized MNPs in imaging β-amyloid deposits and neurofibrillary tangles.
Public/Granted literature
- US20140140932A1 Functionalized Magnetic Nanoparticles and Use in Imaging Amyloid Deposits and Neurofibrillary Tangles Public/Granted day:2014-05-22
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