Invention Grant
- Patent Title: Method of tissue repair using a composite material
- Patent Title (中): 使用复合材料进行组织修复的方法
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Application No.: US14200060Application Date: 2014-03-07
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Publication No.: US09272045B2Publication Date: 2016-03-01
- Inventor: Stacy A. Hutchens , Jonathan Woodward , Barbara R. Evans , Hugh M. O'Neill
- Applicant: UT-Battelle, LLC , University of Tennessee Research Foundation
- Applicant Address: US TN Oak Ridge US TN Knoxville
- Assignee: UT-BATTELLE, LLC,UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION
- Current Assignee: UT-BATTELLE, LLC,UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION
- Current Assignee Address: US TN Oak Ridge US TN Knoxville
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Main IPC: A61K9/16
- IPC: A61K9/16 ; A61K47/38 ; A61L27/46 ; A61L27/56 ; A61K33/42 ; A61K9/50

Abstract:
A composite biocompatible hydrogel material includes a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa. A calcium comprising salt is disposed in at least some of the pores. The porous polymer matrix can comprise cellulose, including bacterial cellulose. The composite can be used as a bone graft material. A method of tissue repair within the body of animals includes the steps of providing a composite biocompatible hydrogel material including a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa, and inserting the hydrogel material into cartilage or bone tissue of an animal, wherein the hydrogel material supports cell colonization in vitro for autologous cell seeding.
Public/Granted literature
- US20140205676A1 METHOD OF TISSUE REPAIR USING A COMPOSITE MATERIAL Public/Granted day:2014-07-24
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