Invention Grant
US09272023B2 Use of ixolaris, a tissue factor inhibitor, for inhibiting angiogenesis
有权
使用组织因子抑制剂ixolaris来抑制血管发生
- Patent Title: Use of ixolaris, a tissue factor inhibitor, for inhibiting angiogenesis
- Patent Title (中): 使用组织因子抑制剂ixolaris来抑制血管发生
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Application No.: US14292232Application Date: 2014-05-30
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Publication No.: US09272023B2Publication Date: 2016-03-01
- Inventor: Ivo M. Francischetti , Robson de Queiroz Monteiro , Jose Marcos C. Ribeiro
- Applicant: The United States of America, as Represented by the Secretary, Department of Health and Human Services
- Applicant Address: US DC Washington
- Assignee: The United States of America, as represented by the Secretary, Department of Health & Human Services
- Current Assignee: The United States of America, as represented by the Secretary, Department of Health & Human Services
- Current Assignee Address: US DC Washington
- Agency: Locke Lord LLP
- Agent Bryan D. Zerhusen
- Main IPC: A61K38/16
- IPC: A61K38/16 ; A61K38/57 ; A61K38/17 ; A61K45/06
Abstract:
The invention provides methods for treatment of tissue factor (TF) mediated or associated diseases or processes, such as cancer, by administering at least an active fragment of an Ixolaris polypeptide to a subject. The invention further includes identification of a subject in need of such treatment, and monitoring a subject for amelioration of at least one sign or symptom of the disease. The invention also features kits.
Public/Granted literature
- US20140342987A1 USE OF IXOLARIS, A TISSUE FACTOR INHIBITOR, FOR THE TREATMENT AND PREVENTION OF CANCER Public/Granted day:2014-11-20
Information query
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