Invention Grant
US09271961B2 Bifunctional AKR1C3 inhibitors/androgen receptor modulators and methods of use thereof
有权
双功能AKR1C3抑制剂/雄激素受体调节剂及其使用方法
- Patent Title: Bifunctional AKR1C3 inhibitors/androgen receptor modulators and methods of use thereof
- Patent Title (中): 双功能AKR1C3抑制剂/雄激素受体调节剂及其使用方法
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Application No.: US14050937Application Date: 2013-10-10
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Publication No.: US09271961B2Publication Date: 2016-03-01
- Inventor: Trevor M. Penning , Adegoke O. Adeniji , Michael C. Burns , Jeffrey Winkler , Barry Twenter
- Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
- Applicant Address: US PA Philadelphia
- Assignee: The Trustees of the University of Pennsylvania
- Current Assignee: The Trustees of the University of Pennsylvania
- Current Assignee Address: US PA Philadelphia
- Agency: Saul Ewing LLP
- Agent Kathryn Doyle; Domingos J. Silva
- Main IPC: A61K31/196
- IPC: A61K31/196 ; C07C229/60 ; A61P35/00 ; A61K31/405 ; A61K31/195 ; A61K31/205 ; A61K45/06 ; C07C229/58
Abstract:
The invention includes compositions comprising selective AKR1C3 inhibitors. The invention also includes compositions comprising bifunctional AKR1C3 inhibitors and selective androgen receptor modulators. The invention further includes methods of treatment using the compositions of the invention.
Public/Granted literature
- US20140107085A1 Bifunctional AKR1C3 Inhibitors/Androgen Receptor Modulators and Methods of Use Thereof Public/Granted day:2014-04-17
Information query
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