An information processing apparatus, a screen output system, a screen output control method, and a program control output are disclosed. The information processing apparatus includes an image acquiring unit, a differential region extracting unit, a designation accepting unit, and an image output unit. The image acquiring unit acquires a first image to be output to a first display. The differential region extracting unit extracts a differential region that differs between the first image and a second image to be output to a second display. The designation accepting unit accepts a designation of whether to output each differential region to the second display. The image output unit incorporates a portion of the first image that corresponds to a differential region for which a designation to output has been accepted into the second image and outputs the updated second image to the second display.