Invention Grant
- Patent Title: Autophagy and phospholipidosis pathway assays
- Patent Title (中): 自噬和磷脂通路测定
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Application No.: US12584958Application Date: 2009-09-14
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Publication No.: US09250249B2Publication Date: 2016-02-02
- Inventor: Wayne Forrest Patton , Jack Coleman , Yuejun Xiang , Praveen Pande , Zaiguo Li
- Applicant: Wayne Forrest Patton , Jack Coleman , Yuejun Xiang , Praveen Pande , Zaiguo Li
- Applicant Address: US NY Farmingdale
- Assignee: Enzo Biochem, Inc.
- Current Assignee: Enzo Biochem, Inc.
- Current Assignee Address: US NY Farmingdale
- Agent Louis M. Heidelberger
- Main IPC: G01N33/68
- IPC: G01N33/68 ; G01N33/50 ; G01N33/58 ; G01N33/94
Abstract:
Provided are assays useful for detecting and monitoring autophagy and phospholipidosis, including the progression of lysosomal storage diseases. Drugs and treatments for lysosomal storage diseases can be monitored for effectiveness in lysosomal storage disease conditions. Drug candidates and suspected toxic agents can also be screened for toxicity to cells, tissues and organs. Also provided are methods for distinguishing between phospholipidosis activators and autophagy pathway perturbation agents.
Public/Granted literature
- US20100093004A1 Autophagy and phospholipidosis pathway assays Public/Granted day:2010-04-15
Information query
IPC分类:
