A hose and fitting assembly includes a hose of a first thermoplastic polymer material having an end portion with an inner surface and an outer surface and a fitting of a second polymer material for connection with an external point of use. The fitting has a central tubular projection with an axial fluid passageway. The central tubular projection has an inner wall which defines the fluid passageway and an outer wall, at least partly integrally coupled to the inner surface of the end portion of the hose. The hose and fitting assembly includes a reinforcement member of a third polymer material at the periphery of the end portion of the hose for restraining radial deformations of the hose and providing the assembly with a good mechanical and/or hydraulic sealing capability. A method of making such assembly.