Invention Grant
- Patent Title: Method for producing epithelial stem cells
- Patent Title (中): 产生上皮干细胞的方法
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Application No.: US14007133Application Date: 2012-03-23
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Publication No.: US09249394B2Publication Date: 2016-02-02
- Inventor: Makoto Hijikata , Hassan Hussein Aly , Tatsuya Yamaguchi
- Applicant: Makoto Hijikata , Hassan Hussein Aly , Tatsuya Yamaguchi
- Applicant Address: JP Kyoto-shi JP Osaka-shi
- Assignee: KYOTO UNIVERSITY,TOYOBO CO., LTD.
- Current Assignee: KYOTO UNIVERSITY,TOYOBO CO., LTD.
- Current Assignee Address: JP Kyoto-shi JP Osaka-shi
- Agency: Westerman, Hattori, Daniels & Adrian, LLP
- Priority: JP2011-067112 20110325
- International Application: PCT/JP2012/057468 WO 20120323
- International Announcement: WO2012/133156 WO 20121004
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/071 ; C12N9/12 ; A61K35/36
Abstract:
An object of this invention is to provide a method, etc., for efficiently proliferating a pluripotent epithelial somatic stem cell. A method for producing an epithelial somatic stem cell comprising Steps (A) and (B) below: (A) expressing a gene of a protein having an activity for causing a cell in G0 phase or G1 phase to enter S phase, in a cell population including an epithelial somatic stem cell; and (B) culturing the cell obtained in Step (A) in the presence of an extracellular growth factor.
Public/Granted literature
- US20140030809A1 METHOD FOR PRODUCING EPITHELIAL STEM CELLS Public/Granted day:2014-01-30
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