Invention Grant
US09249215B2 Human monoclonal antibody against S. aureus derived alpha-toxin and its use in treating or preventing abscess formation
有权
针对金黄色葡萄球菌来源的α-毒素的人单克隆抗体及其在治疗或预防脓肿形成中的用途
- Patent Title: Human monoclonal antibody against S. aureus derived alpha-toxin and its use in treating or preventing abscess formation
- Patent Title (中): 针对金黄色葡萄球菌来源的α-毒素的人单克隆抗体及其在治疗或预防脓肿形成中的用途
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Application No.: US13388254Application Date: 2010-08-10
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Publication No.: US09249215B2Publication Date: 2016-02-02
- Inventor: Michael Rudolf , Holger Koch
- Applicant: Michael Rudolf , Holger Koch
- Applicant Address: US CA San Jose
- Assignee: Aridis Pharmaceuticals, Inc.
- Current Assignee: Aridis Pharmaceuticals, Inc.
- Current Assignee Address: US CA San Jose
- Agency: Quine Intellectual Property Law Group, P.C.
- Agent Gary Baker
- Priority: EP09010311 20090810
- International Application: PCT/EP2010/004884 WO 20100810
- International Announcement: WO2011/018208 WO 20110217
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C12P21/08 ; C12N5/04 ; A61K39/40 ; C12N5/07 ; C12N5/16 ; C12P21/04 ; C12N1/00 ; C07K16/12 ; A61K39/00
Abstract:
The present invention includes a human monoclonal antibody specific for the alpha-toxin of S. aureus, a hybridoma producing it, nucleic acids encoding it, and host cells transfected therewith. Further, the present invention includes methods for producing the monoclonal antibody. In addition, the present invention includes pharmaceutical compositions comprising at least one antibody or at least one nucleic acid encoding the antibody. Further, the present invention includes the use of the monoclonal antibody for treating or preventing abscess formation.
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