Invention Grant
- Patent Title: Treatment of brain injury with a neurotrophic peptide
- Patent Title (中): 用神经营养肽治疗脑损伤
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Application No.: US14325880Application Date: 2014-07-08
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Publication No.: US09249203B2Publication Date: 2016-02-02
- Inventor: Khalid Iqbal , Inge Grundke-Iqbal
- Applicant: The Research Foundation for Mental Hygiene, Inc.
- Applicant Address: US NY Menands
- Assignee: The Research Foundation For Mental Hygiene, Inc.
- Current Assignee: The Research Foundation For Mental Hygiene, Inc.
- Current Assignee Address: US NY Menands
- Agency: Bond Schoeneck & King, PLLC
- Agent David L. Nocilly
- Priority: EP07450050 20070316
- Main IPC: A01N37/18
- IPC: A01N37/18 ; A61K38/16 ; C07K14/475 ; A61K38/08 ; A61K38/18 ; C07K5/103 ; C07K5/113 ; C07K7/06

Abstract:
A neurotrophic peptide having the sequence VGDGGLFEKKL (SEQ ID NO: 1) may be used to help sustain local microenvironment after mild-to-moderate brain injury. Treatment with the peptide was shown to enhance differentiation of newly born progenitors in the dentate gyrus 30 days after injury and to promote neuronal maturation and survival that is not seen naturally after traumatic brain injuries.
Public/Granted literature
- US20150252087A1 TREATMENT OF BRAIN INJURY WITH A NEUROTROPHIC PEPTIDE Public/Granted day:2015-09-10
Information query
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