A multi-spectrum photosensitive device and method for sampling the same, the method includes a first combining process for combining-and-sampling two adjacent pixels in same row different column, or in different row same column, or in different row different column in the pixel array to obtain a sampling data of a first combined pixel; a second combining process for combining-and-sampling the sampling data of the first combined pixel obtained from the first combining unit to obtain a sampling data of a second combined pixel; and a third combining process, a sampling data of a third combined pixel is obtained by a method for color conversion and image scaling in a digital space. The application is applied for a multi-pixel sharing reading and amplifying circuit of a single-layer color photosensitive chip, a single-sided multi-layer photosensitive chip, and a double-sided double-layer photosensitive chip. In the basis of the spirit of the existing pixel reading circuit, the application has orders of magnitude breakthrough in principle, basic circuit and performance, and implements a YUV format output of a sub-sampling image in a photosensitive device at the same time of implementing sub-sampling with high performance.