Invention Grant
US09097707B2 Photoreactive regulator of protein function and methods of use thereof
有权
蛋白质功能的光反应性调节剂及其使用方法
- Patent Title: Photoreactive regulator of protein function and methods of use thereof
- Patent Title (中): 蛋白质功能的光反应性调节剂及其使用方法
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Application No.: US13671908Application Date: 2012-11-08
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Publication No.: US09097707B2Publication Date: 2015-08-04
- Inventor: Ehud Y. Isacoff , Richard H. Kramer , Dirk Trauner , Matthew R. Banghart , Matthew Volgraf , Pablo Ignacio Gorostiza Langa , Katharine Borges
- Applicant: The Regents of the University of California
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Bozicevic, Field & Francis LLP
- Agent Paula A. Borden
- Main IPC: C07C29/56
- IPC: C07C29/56 ; G01N33/53 ; C07K14/705 ; A61K38/00

Abstract:
The present invention provides a synthetic regulator of protein function, which regulator is a light-sensitive regulator. The present invention further provides a light-regulated polypeptide that includes a subject synthetic regulator. Also provided are cells and membranes comprising a subject light-regulated polypeptide. The present invention further provides methods of modulating protein function, involving use of light. The present invention further provides methods of identifying agents that modulate protein function.
Public/Granted literature
- US20130137113A1 Photoreactive Regulator of Protein Function and Methods of Use Thereof Public/Granted day:2013-05-30
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