Invention Grant
- Patent Title: Efficient proliferation method for a kupffer cell and use thereof
- Patent Title (中): 枯否细胞的高效增殖方法及其用途
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Application No.: US13500847Application Date: 2010-10-08
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Publication No.: US09097705B2Publication Date: 2015-08-04
- Inventor: Hiroshi Kitani , Takato Takenouchi , Noriko Yamanaka , Miyako Yoshioka
- Applicant: Hiroshi Kitani , Takato Takenouchi , Noriko Yamanaka , Miyako Yoshioka
- Applicant Address: JP Tsukuba-shi
- Assignee: NATIONAL INSTITUTE OF AGROBIOLOGICAL SCIENCES
- Current Assignee: NATIONAL INSTITUTE OF AGROBIOLOGICAL SCIENCES
- Current Assignee Address: JP Tsukuba-shi
- Agency: Sughrue Mion, PLLC
- Priority: JP2009-235052 20091009
- International Application: PCT/JP2010/067767 WO 20101008
- International Announcement: WO2011/043469 WO 20110414
- Main IPC: C12N5/0786
- IPC: C12N5/0786 ; A61K35/407 ; G01N33/50
Abstract:
The present invention has successfully established a mixed culture system capable of actively proliferating a Kupffer cell in a primary culture of a cell population derived from a liver. Additionally, the present invention has successfully established a novel production method for efficiently producing a large amount of highly purified Kupffer cells using this mixed culture system.
Public/Granted literature
- US20120202197A1 EFFICIENT PROLIFERATION METHOD FOR A KUPFFER CELL AND USE THEREOF Public/Granted day:2012-08-09
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