Invention Grant
- Patent Title: Kinase inhibitors and methods of use thereof
- Patent Title (中): 激酶抑制剂及其使用方法
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Application No.: US14052661Application Date: 2013-10-11
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Publication No.: US09096594B2Publication Date: 2015-08-04
- Inventor: Florence Fevrier Wagner , Jennifer Q. Pan , Sivaraman Dandapani , Andrew Germain , Edward Holson , Benito Munoz , Partha P. Nag , Michel Weiwer , Michael C. Lewis , Stephen J. Haggarty , Joshua A. Bishop , Kimberly Stegmaier , Versha Banerji
- Applicant: The Broad Institute, Inc. , The General Hospital Corporation , Dana-Farber Cancer Institute, Inc.
- Applicant Address: US MA Cambridge US MA Boston US MA Boston
- Assignee: The Broad Institute, Inc.,The General Hospital Corporation,Dana-Farber Cancer Institute, Inc.
- Current Assignee: The Broad Institute, Inc.,The General Hospital Corporation,Dana-Farber Cancer Institute, Inc.
- Current Assignee Address: US MA Cambridge US MA Boston US MA Boston
- Agency: Wolf, Greenfield & Sacks, P.C.
- Agent C. Hunter Baker; Wei Zhang
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D471/10
Abstract:
The present invention provides compounds of formula I, pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting kinase (e.g., GSK3 (e.g., GSK3α or GSK3β) or CK1) activity. The present invention further provides methods of using the compounds described herein for treating kinase-mediated disorders, such as neurological diseases, psychiatric disorders, metabolic disorders, and cancer.
Public/Granted literature
- US20140107141A1 KINASE INHIBITORS AND METHODS OF USE THEREOF Public/Granted day:2014-04-17
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