Invention Grant
- Patent Title: Targets for regulation of angiogenesis
- Patent Title (中): 血管生成调控目标
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Application No.: US14222926Application Date: 2014-03-24
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Publication No.: US09073982B2Publication Date: 2015-07-07
- Inventor: Nancy Klauber DeMore , Cam Patterson , Rajendra Bhati , Bradley G. Bone
- Applicant: The University of North Carolina at Chapel Hill
- Applicant Address: US NC Chapel Hill
- Assignee: The University of North Carolina at Chapel Hill
- Current Assignee: The University of North Carolina at Chapel Hill
- Current Assignee Address: US NC Chapel Hill
- Agency: Myers Bigel Sibley & Sajovec, P.A.
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C12P21/08 ; C07K16/00 ; A61K38/00 ; C07K16/18 ; A61K38/13 ; C07K16/28 ; C07K16/40 ; C12N15/113 ; G01N33/574

Abstract:
The present invention relates to the identification of polynucleotides and polypeptides having increased expression in tumor blood vessels. The invention further relates to the use of the identified polynucleotides and polypeptides, and inhibitors of the polynucleotides and polypeptides, in the regulation of angiogenesis and the diagnosis and treatment of angiogenesis-related diseases such as cancer.
Public/Granted literature
- US20140294848A1 Novel Targets for Regulation of Angiogenesis Public/Granted day:2014-10-02
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