Invention Grant
- Patent Title: Oligonucleotide conjugates
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Application No.: US13892065Application Date: 2013-05-10
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Publication No.: US09072790B2Publication Date: 2015-07-07
- Inventor: Sergei M. Gryaznov , Krisztina Pongracz , Richard L. Tolman , Gregg B. Morin
- Applicant: Geron Corporation
- Applicant Address: US CA Menlo Park
- Assignee: Geron Corporation
- Current Assignee: Geron Corporation
- Current Assignee Address: US CA Menlo Park
- Agency: Bozicevic, Field & Francis LLP
- Agent Carol L. Francis; Glenn J. Foulds
- Main IPC: A61K47/48
- IPC: A61K47/48 ; C07H21/00
Abstract:
Oligonucleotide conjugates, where an oligonucleotide is covalently attached to an aromatic system, are provided. In particular embodiments the oligonucleotide is complementary to the RNA component of human telomerase and is covalently attached to a nucleobase via an optional linker. The conjugates inhibit telomerase enzyme activity.
Public/Granted literature
- US20130253042A1 Oligonucleotide Conjugates Public/Granted day:2013-09-26
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