Invention Grant
- Patent Title: Method of predicting a predisposition to QT prolongation
- Patent Title (中): 预测QT延长倾向的方法
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Application No.: US13263077Application Date: 2010-04-05
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Publication No.: US09072742B2Publication Date: 2015-07-07
- Inventor: Christian Lavedan , Simona Volpi , Louis Licamele
- Applicant: Christian Lavedan , Simona Volpi , Louis Licamele
- Applicant Address: US DC Washington
- Assignee: Vanda Pharmaceuticals, Inc.
- Current Assignee: Vanda Pharmaceuticals, Inc.
- Current Assignee Address: US DC Washington
- Agency: Hoffman Warnick LLC
- International Application: PCT/US2010/029945 WO 20100405
- International Announcement: WO2010/117943 WO 20101014
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; A61K31/519
Abstract:
The present invention describes an association between genetic polymorphisms in the BAI3 gene and a predisposition to prolongation of the QT interval, and provides related methods for the prediction of such a predisposition, the administration of QT interval-prolonging compounds to individuals having such a predisposition, and determining whether a compound is capable of inducing QT prolongation.
Public/Granted literature
- US20120059035A1 METHOD OF PREDICTING A PREDISPOSITION TO QT PROLONGATION Public/Granted day:2012-03-08
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