An imaging system comprises a plurality of imaging detectors for acquiring imaging data. The plurality of imaging detectors is configurable to be arranged proximate to an anatomy of interest within a patient. Each of the plurality of imaging detectors has a field of view (FOV) and at least a portion of the plurality of imaging detectors image the anatomy of interest within the respective FOV. A processor receives the imaging data and processes the imaging data to form a multi-dimensional dataset having at least three dimensions.