Embodiments of a system and method for synchronizing chains in a transceiver using central synchronization signals are generally described herein. In some embodiments, an RF signal having a reference frequency in a differential mode and a synchronization signal having a second frequency being the reference frequency divided by an integer in a common mode are produced at a oscillator generation circuit. The RF signal having a reference frequency in a differential mode and the synchronization signal having a second frequency being the reference frequency divided by an integer in a common mode are provided over each of a plurality of LO lines to a plurality of local LO generation circuit chains. Each synchronization signal having a second frequency being the reference frequency divided by an integer in a common mode is extracted at the plurality of local LO generation circuit chains. A phase of each RF signal having a reference frequency in a differential mode is synchronized in each of the plurality of local LO generation circuit chains using each extracted synchronization signal having a second frequency being the reference frequency divided by an integer in a common mode.