A touch sensing device is provided. The touch sensing device includes a multiplexer and a control unit, and is electrically connected to a touch panel. The touch panel includes a plurality of first-direction electrodes; a plurality of second-direction electrodes; and a dielectric layer, for generating at least one electric field change corresponding to at least one touch point in response to the at least one touch point. The at least one electric field change is generated at an overlapping region of the first-direction and second-direction electrodes. The multiplexer is electrically connected to the touch panel via the first-direction and second-direction electrodes, and selectively performs voltage driving or voltage sensing for the first-direction and second-direction changes a control signal to be transmitted to the multiplexer and receives a sense signal from the multiplexer.