Invention Grant
US09051306B2 Indirubin derivative having highly selective cytotoxicity for malignant tumors
有权
靛玉红衍生物对恶性肿瘤具有高选择性细胞毒性
- Patent Title: Indirubin derivative having highly selective cytotoxicity for malignant tumors
- Patent Title (中): 靛玉红衍生物对恶性肿瘤具有高选择性细胞毒性
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Application No.: US14232836Application Date: 2012-07-05
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Publication No.: US09051306B2Publication Date: 2015-06-09
- Inventor: Takashi Suzuki , Shinichi Miyairi , Hiroaki Saito , Keiichi Tabata
- Applicant: Takashi Suzuki , Shinichi Miyairi , Hiroaki Saito , Keiichi Tabata
- Applicant Address: JP Tokyo
- Assignee: NIHON UNIVERSITY
- Current Assignee: NIHON UNIVERSITY
- Current Assignee Address: JP Tokyo
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2011-156299 20110715
- International Application: PCT/JP2012/067153 WO 20120705
- International Announcement: WO2013/011841 WO 20130124
- Main IPC: C07D405/14
- IPC: C07D405/14 ; A61K31/336
Abstract:
An agent for treating malignant tumors based on a new mechanism is provided, which comprises an indirubin derivative represented by formula (1) or a salt thereof: wherein A represents an alkylene group having 1 to 4 carbon atoms, and R1 to R4 each independently represent a hydrogen atom, a halogen atom, a hydroxy group, or an alkoxy group.
Public/Granted literature
- US20140200253A1 INDIRUBIN DERIVATIVE HAVING HIGHLY SELECTIVE CYTOTOXICITY FOR MALIGNANT TUMORS Public/Granted day:2014-07-17
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