A method of manufacturing wire comprising aluminum oxide particles formed in situ in a fully dense matrix of titanium aluminide intermetallic material by means of the combustion synthesis of aluminum and titanium oxide followed by thermo-mechanical forming. The pre-combustion aluminum may be elemental, or an aluminum alloy containing one or more of the elements vanadium, niobium, molybdenum, or boron. The preferred embodiment of the present invention is an electric power transmission cable comprising a plurality of wires manufactured according to the present invention.