Provided is a medical image processing device capable of determining a state of an obtained brain image and adjusting the obtained image to suit for performing tissue separation processing. The medical image processing device is configured to select a slice image to be processed as a target slice image from a brain image configured by a plurality of slice images, performs processing for measuring an effective maximum value in the cerebral parenchyma, an effective maximum value in a whole image, and a peak average value around the skull with respect to the selected target slice to determine necessity of high-signal-value-control processing based on the measured effective maximum value in the cerebral parenchyma, the effective maximum value in a whole image, and the peak average value around the skull so that when it is determined that the high-signal-value-control processing is necessary, the high-signal-value-control processing is performed to the brain image.