Invention Grant
US09035073B2 3-phenyl-3-methoxy-pyrrolidine derivatives useful as modulators of cortical catecholaminergic neurotransmission
有权
3-苯基-3-甲氧基 - 吡咯烷衍生物，可用作皮质儿茶酚胺能神经传递的调节剂
- Patent Title: 3-phenyl-3-methoxy-pyrrolidine derivatives useful as modulators of cortical catecholaminergic neurotransmission
- Patent Title (中): 3-苯基-3-甲氧基 - 吡咯烷衍生物，可用作皮质儿茶酚胺能神经传递的调节剂
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Application No.: US14160901Application Date: 2014-01-22
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Publication No.: US09035073B2Publication Date: 2015-05-19
- Inventor: Clas Sonesson , Lars Swanson , Fredrik Pettersson
- Applicant: INTEGRATIVE RESEARCH LABORATORIES SWEDEN AB
- Applicant Address: SE Göteborg
- Assignee: Integrative Research Laboratories Sweden AB
- Current Assignee: Integrative Research Laboratories Sweden AB
- Current Assignee Address: SE Göteborg
- Agency: Ballard Spahr LLP
- Priority: DKPA200801657 20081124
- Main IPC: C07D207/12
- IPC: C07D207/12 ; A61K31/40
Abstract:
The present invention relates to novel 3-phenyl-3-methoxy-pyrrolidine derivatives, useful for modulating extracellular levels of catecholamines, dopamine and norepinephrine, in cerebral cortical areas of the mammalian brain, and more specifically for the treatment of central nervous system disorders. In other aspects the invention relates to pharmaceutical compositions comprising the 3-phenyl-3-methoxy-pyrrolidine derivatives of the invention and to the use of these compounds for therapeutic applications.
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