Invention Grant
- Patent Title: Phosphohistidine analogs
- Patent Title (中): 磷酸组氨酸类似物
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Application No.: US13825699Application Date: 2011-09-23
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Publication No.: US09035068B2Publication Date: 2015-05-19
- Inventor: Tom W. Muir , Jung-Min Kee
- Applicant: Tom W. Muir , Jung-Min Kee
- Applicant Address: US NY New York
- Assignee: THE ROCKEFELLER UNIVERSITY
- Current Assignee: THE ROCKEFELLER UNIVERSITY
- Current Assignee Address: US NY New York
- Agency: Scully, Scott, Murphy & Presser, P.C.
- International Application: PCT/US2011/052854 WO 20110923
- International Announcement: WO2012/040523 WO 20120329
- Main IPC: C07D249/04
- IPC: C07D249/04 ; A61K47/48 ; A61K31/675 ; C07F9/6518 ; C07F9/40
Abstract:
The present invention relates to the phosphohistidine analogs of the present invention which of the formula (I) and the hapten containing the residue of same. It also relates to the hapten conjugated to a carrier molecule and the isolated antibodies raised against the immunogens, said antibodies recognizing polypeptide containing a phosphorylated histidine or the phosphotriazole residue but it does not recognize an amino acid or polypeptide that is not phosphorylated or a polypeptide which is phosphorylated on amino acids other than histidine but not on histidine.
Public/Granted literature
- US20130260398A1 PHOSPHOHISTIDINE ANALOGS Public/Granted day:2013-10-03
Information query
