Invention Grant
- Patent Title: Synthesis of iodixanol in propyleneglycol
- Patent Title (中): 丙二醇中碘克沙醇的合成
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Application No.: US12621556Application Date: 2009-11-19
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Publication No.: US08969619B2Publication Date: 2015-03-03
- Inventor: Hanne Jorunn H. Johnsen , Lars Terje Holmaas , Trond Kjernli , Ole Magne Homestad
- Applicant: Hanne Jorunn H. Johnsen , Lars Terje Holmaas , Trond Kjernli , Ole Magne Homestad
- Applicant Address: NO Oslo
- Assignee: GE Healthcare AS
- Current Assignee: GE Healthcare AS
- Current Assignee Address: NO Oslo
- Main IPC: C07C233/64
- IPC: C07C233/64 ; C07C231/12
Abstract:
This invention relates to the synthesis of iodixanol (1,3-bis(acetamido)-N,N′-bis[3,5-bis(2,3-dihydroxypropylaminocarbonyl)-2,4,6-triiodophenyl]-2-hydroxypropane), more specifically to the dimerisation of 5-acetamido-N,N′-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-isophthalamide with propyleneglycol as solvent.
Public/Granted literature
- US20110021830A1 SYTNHESIS OF IODIXANOL IN PROPYLENEGLYCOL Public/Granted day:2011-01-27
Information query
