A set of handheld, adjustable panels including a plurality of ergonomic keys which function as a keyboard and mouse to allow a user to easily input data to an electronic device. The handheld keyboard and mouse includes two handheld components. Each component comprises a base that fits into the user's palm, a plurality of adjustable finger panels, and an adjustable thumb portion adjacent to the finger panels. The finger panels include a plurality of keys so as to function as a keyboard, and the thumb portion also includes a plurality of keys and acts like a mouse. Each component may also include clips or straps for securing the component to the user's hand, as well as a stand for supporting the component when it is not in use. In addition, at least one of the components may include a display means.