Invention Grant
- Patent Title: Phthalazine derivatives as PARP inhibitors
- Patent Title (中): 酞嗪衍生物作为PARP抑制剂
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Application No.: US12856218Application Date: 2010-08-13
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Publication No.: US08946221B2Publication Date: 2015-02-03
- Inventor: Laurence Anne Mevellec , Ludo E. J. Kennis , Josephus Carolus Mertens , Jacobus A. J. Van Dun , Maria V. F. Somers , Walter B. L. Wouters
- Applicant: Laurence Anne Mevellec , Ludo E. J. Kennis , Josephus Carolus Mertens , Jacobus A. J. Van Dun , Maria V. F. Somers , Walter B. L. Wouters
- Applicant Address: BE Beerse
- Assignee: Janssen Pharmaceutica, NV
- Current Assignee: Janssen Pharmaceutica, NV
- Current Assignee Address: BE Beerse
- Main IPC: C07D237/30
- IPC: C07D237/30 ; C07D237/34 ; A61K31/502 ; C07D417/14 ; C07D513/04 ; C07D405/14 ; C07D401/04 ; C07D471/04 ; C07D401/12 ; C07D403/12 ; C07D401/14 ; A61P9/10 ; A61P25/08 ; A61P25/28 ; A61P25/18
Abstract:
The present invention provides compounds of formula (I), their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I) wherein R1, R2, L1, L2, X, Y, Q and Z have defined meanings.
Public/Granted literature
- US20110065684A1 PHTHALAZINE DERIVATIVES AS PARP INHIBITORS Public/Granted day:2011-03-17
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