A method of transmitting control information in a wireless communication system is provided. The method includes configuring downlink control information including a plurality of information fields according to a format of scheduling for transmission of a single codeword in a spatial multiplexing mode, wherein the plurality of information fields include a precoding matrix indicator (PMI) confirmation filed for indicating whether precoding is performed on downlink data by using a PMI reported by a user equipment and a transmitted precoding matrix indicator (TPMI) information field for indicating a codebook index, and at least one of the PMI confirmation field and the TPMI information field indicates an offset value of power for the downlink data transmission or interference information for the downlink data transmission, and transmitting the downlink control information.