Embodiments herein advantageously reduce the amount of control signalling and header information that must accompany an application layer message when transporting that message from a wireless device to a supporting application server via an intermediate node. To do so, the wireless device prepares a single radio block that includes the application layer message and an indication that the single radio block contains the entire application layer message. The device then sends a control message to the intermediate node that requests allocation of radio resources for sending the single radio block without establishing a temporary block flow (TBF). The device finally sends the single radio block using the allocated resources, without a TBF. Upon receiving the block, the intermediate node determines, based on the indication within the block, whether or not the block contains an entire application layer message. If so, the intermediate node forwards that application layer message towards the application server.