An impedance measurement circuit comprises a current source arrangement, a voltage measurement arrangement and a processor. The circuit is operable in a two-point measurement mode and a four-point measurement mode and the processor is adapted to derive the impedance to be measured by combining the measurement voltages from the two-point and the four-point measurement modes. This combines the results of both two-point and four-point measurement techniques to provide improved accuracy. In particular, the two results enable the effect of the electrode resistance to be cancelled.