Invention Grant
- Patent Title: 3′,6-substituted indirubins and their biological applications
- Patent Title (中): 3'，6-取代的靛玉红及其生物应用
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Application No.: US12737640Application Date: 2009-07-21
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Publication No.: US08829203B2Publication Date: 2014-09-09
- Inventor: Laurent Meijer , Leandros Skaltsounis , Emmanuel Mikros , Prokopios Magiatis , Carl Johnson
- Applicant: Laurent Meijer , Leandros Skaltsounis , Emmanuel Mikros , Prokopios Magiatis , Carl Johnson
- Applicant Address: FR Paris Cedex
- Assignee: Centre National de la Recherche Scientifique (CNRS)
- Current Assignee: Centre National de la Recherche Scientifique (CNRS)
- Current Assignee Address: FR Paris Cedex
- Agency: Nixon & Vanderhye P.C.
- Priority: EP08161646 20080801
- International Application: PCT/IB2009/053153 WO 20090721
- International Announcement: WO2010/013168 WO 20100204
- Main IPC: C09B7/04
- IPC: C09B7/04
Abstract:
Indirubin derivatives of formula (I) wherein R represents -(A)n- R1 or —CO—N(R2,R3) with •A being C1-C5 alkylene group, optionally substituted by one or several A1 radical, A1 being an halogen Br, OH, OR4 or NH2, R4 being C1-C5 alkyl; —R1 being halogen, OH, N(R2, R3); R2 and R3, identical or different, being C1-C5 alkyl, optionally substituted by A1 such as above defined, or R2 and R3 are part of a cycle with 5 or 6 elements optionally comprising another heteroatom such as O or N; •n=1−5. It also relates to the biological application thereof.
Public/Granted literature
- US20110136808A1 3',6-SUBSTITUTED INDIRUBINS AND THEIR BIOLOGICAL APPLICATIONS Public/Granted day:2011-06-09
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