Invention Grant
US08829031B2 Indole derivative modulators of the alpha 7 nAChR 有权
alpha 7 nAChR的吲哚衍生物调节剂

  • Patent Title: Indole derivative modulators of the alpha 7 nAChR
  • Patent Title (中): alpha 7 nAChR的吲哚衍生物调节剂
  • Application No.: US13263370
    Application Date: 2010-04-14
  • Publication No.: US08829031B2
    Publication Date: 2014-09-09
  • Inventor: Kevin Dinnell
  • Applicant: Kevin Dinnell
  • Applicant Address: GB London
  • Assignee: Proximagen Ltd.
  • Current Assignee: Proximagen Ltd.
  • Current Assignee Address: GB London
  • Agency: Banner & Witcoff, Ltd.
  • International Application: PCT/EP2010/054910 WO 20100414
  • International Announcement: WO2010/119078 WO 20101021
  • Main IPC: A61K31/4439
  • IPC: A61K31/4439 C07D401/14
Indole derivative modulators of the alpha 7 nAChR
Abstract:
This invention relates to modulation of the α7 nicotinic acetylcholine receptor (nAChR) by a compound of formula (I) or a salt thereof: wherein R1 is imidazolyl, pyridinyl or pyrimidinyl, any of which is optionally substituted by one group independently selected from C1-3alkyl and C1-3alkoxy.
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