Invention Grant
US08828652B2 Elimination of N-glycolylneuraminic acid from animal products for human use
有权
从用于人类的动物产品中消除N-羟乙酰神经氨酸
- Patent Title: Elimination of N-glycolylneuraminic acid from animal products for human use
- Patent Title (中): 从用于人类的动物产品中消除N-羟乙酰神经氨酸
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Application No.: US13965880Application Date: 2013-08-13
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Publication No.: US08828652B2Publication Date: 2014-09-09
- Inventor: Ajit Varki , Anna Maria Hedlund , Dzung Nguyen
- Applicant: The Regents of The University of California
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Medlen & Carroll, LLP
- Main IPC: A01N1/00
- IPC: A01N1/00 ; A01N1/02 ; C12N15/00 ; C12N5/00 ; C12N5/02 ; A01K67/027 ; A01N63/00 ; A61K48/00 ; C12N15/85 ; A61K8/98 ; C12N9/02
Abstract:
The application is in the field of transgenic (non-human) organisms, sialic acid chemistry, metabolism and antigenicity. More particularly, the invention is related to a method to produce Neu5Gc-free animals and products therefrom comprising disrupting the CMAH gene and thereby reducing or eliminating Neu5Gc from biological material of non-humans.
Public/Granted literature
- US20140044798A1 Elimination of N-Glycolylneuraminic Acid From Animal Products For Human Use Public/Granted day:2014-02-13
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