Invention Grant
- Patent Title: Silent Fc variants of anti-CD40 antibodies
- Patent Title (中): 抗CD40抗体的沉默Fc变体
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Application No.: US13295141Application Date: 2011-11-14
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Publication No.: US08828396B2Publication Date: 2014-09-09
- Inventor: Christoph Heusser , James Rush , Karen Vincent
- Applicant: Christoph Heusser , James Rush , Karen Vincent
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28 ; A61K39/00

Abstract:
The present invention relates to silent Fc variants of anti-CD40 antibodies and compositions and methods of use of said antibodies for treating pathological disorders such as autoimmune and inflammatory disorders and/or for preventing or reducing the risk of graft rejection in transplantation.
Public/Granted literature
- US20120121585A1 SILENT Fc VARIANTS OF ANTI-CD40 ANTIBODIES Public/Granted day:2012-05-17
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