Invention Grant
US08796238B2 Short RNA mimetics 有权
短RNA模拟物

  • Patent Title: Short RNA mimetics
  • Patent Title (中): 短RNA模拟物
  • Application No.: US13496772
    Application Date: 2010-09-13
  • Publication No.: US08796238B2
    Publication Date: 2014-08-05
  • Inventor: Kevin Forbes
  • Applicant: Kevin Forbes
  • Applicant Address: US MO St. Louis
  • Assignee: Sigma-Aldrich Co. LLC
  • Current Assignee: Sigma-Aldrich Co. LLC
  • Current Assignee Address: US MO St. Louis
  • Agency: Polsinelli PC
  • International Application: PCT/US2010/048597 WO 20100913
  • International Announcement: WO2011/034811 WO 20110324
  • Main IPC: C12N15/11
  • IPC: C12N15/11
Short RNA mimetics
Abstract:
The present invention provides synthetic oligonucleotides that mimic the function of short RNAs such as, for example, microRNAs or short interfering RNAs. In particular, the synthetic oligonucleotides comprise a duplex region comprising an unpaired bulge in one of the strands.
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