Invention Grant
- Patent Title: Stabilized formulations containing anti-PCSK9 antibodies
- Patent Title (中): 稳定的含有抗PCSK9抗体的制剂
-
Application No.: US13559862Application Date: 2012-07-27
-
Publication No.: US08795669B2Publication Date: 2014-08-05
- Inventor: Scott Walsh , Daniel Dix
- Applicant: Scott Walsh , Daniel Dix
- Applicant Address: US NY Tarrytown
- Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee Address: US NY Tarrytown
- Agency: Swanson & Bratschun, L.L.C.
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K38/00 ; C07K16/00
Abstract:
The present invention provides pharmaceutical formulations comprising a human antibody that specifically binds to human proprotein convertase subtilisin/kexin type 9 (PCSK9). The formulations may contain, in addition to an anti-PCSK9 antibody, at least one amino acid, at least one sugar, or at least one non-ionic surfactant. The pharmaceutical formulations of the present invention exhibit a substantial degree of antibody stability after storage for several months.
Public/Granted literature
- US20130189277A1 Stabilized Formulations Containing Anti-PCSK9 Antibodies Public/Granted day:2013-07-25
Information query
