A delivery mechanism for delivering tissue holding implants through tissues to be held in approximation includes a shaft having a tip at its distal end, and which is loaded with one or more implants. A wire channel which contains a driving wire is also located within the shaft. When the mechanism is actuated, the driving wire exhibits a proportional longitudinal displacement in the wire channel, such that the wire engages an implant, conveys it along the shaft's longitudinal axis towards the tip, and forces it through the tip. The implants are oriented such that they lie along or nearly along the shaft's longitudinal axis when being conveyed along the axis. The mechanism may optionally include an opposing jaw arranged such that, when actuated, the distal end of the jaw is moved towards the tip, such that tissues placed between the jaw and tip are pinned between them.