A case for a mobile electronic device with a touch screen is provided. The case comprises a base frame and first and second frames. The base frame contacts the back of the mobile electronic device and includes coupling parts at the periphery thereof. The first frame wraps one widthwise side and both lengthwise sides, over a certain distance, of the mobile electronic device. The second frame wraps the other widthwise side and both lengthwise sides, over the remaining distance except the distance of lengthwise sides wrapped by the first frame. The first and second frames comprise guard parts for wrapping part of the periphery of the front of the mobile electronic device. The base frame is coupled to the first and second frames by the coupling parts, thereby wrapping the back, widthwise and lengthwise sides, of the mobile electronic device.