The present invention relates to the field of communication technology, and a de-registration method, a Home NodeB (HNB) and a Home NodeB Gateway (HNB GW) are disclosed. In an embodiment, the present invention provides a de-registration method, comprising: initiating, by an HNB GW, release of pre-registration resources corresponding to user equipment (UE) after the HNB GW receives indication information indicating that the UE moves to another cell from a source HNB. Applying the embodiment of the present invention can release pre-registration resources in time and reduce waste of resources.