Invention Grant
US08691227B2 Methods of treating multiple sclerosis, rheumatoid arthritis and inflammatory bowel disease using agonists antibodies to PILR-α
有权
使用PILR-α的激动剂抗体治疗多发性硬化，类风湿性关节炎和炎症性肠病的方法
- Patent Title: Methods of treating multiple sclerosis, rheumatoid arthritis and inflammatory bowel disease using agonists antibodies to PILR-α
- Patent Title (中): 使用PILR-α的激动剂抗体治疗多发性硬化，类风湿性关节炎和炎症性肠病的方法
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Application No.: US13516635Application Date: 2010-12-10
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Publication No.: US08691227B2Publication Date: 2014-04-08
- Inventor: Cristina M. Tato , Barbara Joyce-Shaikh , Daniel J. Cua
- Applicant: Cristina M. Tato , Barbara Joyce-Shaikh , Daniel J. Cua
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Gregory R. Bellomy
- International Application: PCT/US2010/059893 WO 20101210
- International Announcement: WO2011/084357 WO 20110714
- Main IPC: A61K39/00
- IPC: A61K39/00
Abstract:
The present invention provides methods of using PILRα agonists, or PILRβ antagonists, to treat immune disorders, such as autoimmune and inflammatory disorders, including CNS, joint and gut inflammation.
Public/Granted literature
- US20130071380A1 MODULATION OF PILR TO TREAT IMMUNE DISORDERS Public/Granted day:2013-03-21
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