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US08689460B2 Optimization of nucleation and crystallization for lyophilization using gap freezing 有权
使用间隙冷冻优化冷冻干燥的成核和结晶

Optimization of nucleation and crystallization for lyophilization using gap freezing
Abstract:
This application discloses devices, articles, and methods useful for producing lyophilized cakes of solutes. The devices and articles provide for a method of freezing liquid solutions of the solute by the top and the bottom of the solution simultaneously. The as frozen solution then provides a lyophilized cake of the solutes with large and uniform pores.
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