Disclosed are representative examples of methods, apparatus, and systems for generating test patterns targeting multiple faults using Boolean Satisfiability (SAT)-based test pattern generation methods. A SAT instance is constructed based on the circuit design information and a set of faults being targeted. A SAT solving engine is applied to the SAT instance to search for a test pattern for detecting the set of faults. The SAT instance or the SAT solving engine may be modified so that the SAT solving engine will search for a test pattern for detecting a maximum number of faults in the set of faults.