An RF connection matrix may include first and second carrier-specific RF connection matrix modules. The first carrier-specific RF connection matrix module can be adapted to route a first downlink transmission to one or more remote antenna units for transmission on a first carrier. The second carrier-specific RF connection matrix module can be adapted to route a second downlink transmission to one or more remote antenna units for transmission on a second carrier. Methods for facilitating simulcasting and de-simulcasting may include receiving a signal associated with a sector ID, which signal includes a first downlink transmission for a first carrier and a second downlink transmission for a second carrier. The first downlink transmission can be routed to one or more remote antenna units for transmission on the first carrier. The second downlink transmission can be routed to one or more remote antenna units for transmission on the second carrier.