According to one embodiment, a visual detection system includes an image processing unit coupled to a display and one or more neuro-physiological sensors. The display generates an image that may be viewed by a user. The neuro-physiological sensors generate neuro-physiological signals representing neuro-physiological characteristics of the user while viewing the display. The image processing unit receives the neuro-physiological signals from the neuro-physiological sensors, determines a region of interest in the image according to the neuro-physiological signals, and provides an indication of the presence of the region of interest in the image.