A flexible circuit assembly that includes a flexible circuit substrate. A spacer is attached to a first side surface of the substrate, and a die carrier is attached to the opposite side surface of the substrate. The die carrier includes one or more photonic die mounted thereon that face an opening formed through the substrate so that the photonic die transmits and/or receives optical signals through the opening. Wire bonds electrically connect the photonic die to an electrical pad on the first side surface of the substrate. The spacer helps to space the wire bonds from an optical connector that connects to the flexible circuit assembly, so that the wire bonds do not interfere with the mechanical connection between the flexible circuit assembly and the optical connector.