A reference pixel memory storage space configuration method for configuring a main storage sub-space and an extra storage sub-space of a reference pixel memory storage space of a high resolution digital image capturing apparatus is disclosed. The method includes steps of: calculating a first frame to obtain a plurality of first reconstruction reference pixels; storing the first reconstruction reference pixels in the main storage sub-space; moving a search range window to search the first reconstruction reference pixels and calculating a second frame by referencing the first reconstruction reference pixels covered by the search range window to obtain a plurality of second reconstruction reference pixels, and when the search range window is moved from a first region to a second region in the main storage sub-space, the first region becomes an available space. The second reconstruction reference pixels are orderly stored in the extra storage sub-space and the available space.